Twenty years of research have led to the
creation of ULTIMUNE. Now your skin can reclaim the
strength to fight all kinds of damage on its own.
Make strong, beautiful skin your reality, now and over time.

Beauty brings out
the strength within.

Ultimune Power Infusing Concentrate

Engineered with ImuGeneration Technology™*. 25 years of research.
One fierce defender. Continuously bolsters skin’s ability to fortify itself from within.
#Ultimune. Made for inner skin defenses. Made with soul.

*Innate Multifunction Unlocking Next Generation Technology

  • Just one week after using it:
  • 87% of women felt their skin had become stronger.*
  • 88% of women felt their skin had become more resilient.*
  • 80% of women felt their skin had never looked healthier.*

*Based on 106 respondents after 1 week of use.

Smooth. Firm.
Resilient. Strengthen
your skin from within.

ImuGeneration Technology™*

Discover how you can keep generating inner skin defenses, even when you’re in a harsh environment. ImuGeneration Technology™* uses potent natural extracts to encourage skin’s ability to defend its own ideal condition, defying concerns now, and over time.

Ultimune Power Infusing Concentrate

*Innate Multifunction Unlocking Next Generation Technology

Smoother. Stronger.
More resilient
day by day.

Skin's multi-defensive power can decline significantly in the delicate eye area over time. Inspired by Shiseido's research on the skin's own systems, Ultimune Power Infusing Eye Concentrate helps visibly reduce major signs of aging, making even bare skin dewier, smoother and more supple.

Ultimune Power Infusing Eye Concentrate

Beauty is a skincare ritual.
Discover yours.

Shiseido believes that the secret to beauty lies within the skin's own natural defensive and regenerative powers. After years of research, we've developed a holistic approach to channeling these powers, for skin that resists problems and improves its own condition, now and in the future. As its beauty is reignited from within, your skin reaches its full potential.

Essential Energy Moisturizing Cream